(3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b ]oxazol-5(7a H)-one
- CAS NO.:143140-06-1
- Empirical Formula: C13H13NO2
- Molecular Weight: 215.25
- MDL number: MFCD00274331
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:49:08
What is (3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b ]oxazol-5(7a H)-one?
Chemical properties
cream crystalline powder
The Uses of (3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b ]oxazol-5(7a H)-one
High levels of asymmetric induction have been obtained with this chiral bicyclic lactam in cycloadditions, alkylations, conjugate additions, annulations, and dihydroxylations.
Properties of (3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b ]oxazol-5(7a H)-one
| Melting point: | 88-92 °C |
| Boiling point: | 355.53°C (rough estimate) |
| Density | 1.1242 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| pka | -1.90±0.60(Predicted) |
| optical activity | [α]20/D +124°, c = 1 in chloroform |
| CAS DataBase Reference | 143140-06-1 |
Safety information for (3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b ]oxazol-5(7a H)-one
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for (3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b ]oxazol-5(7a H)-one
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2-Amino-5-bromo-4-(trifluoromethyl)pyridine Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran




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