3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE

Synonym(s):3α,7α,12α-Trihydroxy-5β-cholan-24-oylglycine amidohydrolase

CAS NO.：37289-07-9
Molecular Weight: 0
MDL number: MFCD00130789
Update Date: 2026-05-27 17:34:12

What is 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE?

The Uses of 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE

The enzyme from Sigma has been used in the analysis of bile samples in various studies.

Biochem/physiol Actions

The enzyme is an N-terminal nucleophilic (Ntn) hydrolase that catalyzes the hydrolysis of amide bonds, liberates the glycine/taurine moiety from the steroid core and eventually yields unconjugated bile acids. Agents that oxidize thiol groups (e.g., p-mercuribenzoate, iodoacetamide, Hg2+, Cu2+, and Cd2+) have been shown to strongly inhibit bile salt hydrolase (BSH) activity in Clostridium perfringens.

Properties of 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE

storage temp.	-20°C
form	lyophilized powder

Safety information for 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE

Computed Descriptors for 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OYLGLYCINE AMIDOHYDROLASE

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