3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine amidohydrolase
Synonym(s):3α,7α,12α-Trihydroxy-5β-cholan-24-oylglycine amidohydrolase
- CAS NO.：37289-07-9
- Molecular Weight: 0
- MDL number: MFCD00130789
- Update Date: 2026-09-12 18:48:05
What is 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine amidohydrolase?
The Uses of 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine amidohydrolase
The enzyme from Sigma has been used in the analysis of bile samples in various studies.
Biochem/physiol Actions
The enzyme is an N-terminal nucleophilic (Ntn) hydrolase that catalyzes the hydrolysis of amide bonds, liberates the glycine/taurine moiety from the steroid core and eventually yields unconjugated bile acids. Agents that oxidize thiol groups (e.g., p-mercuribenzoate, iodoacetamide, Hg2+, Cu2+, and Cd2+) have been shown to strongly inhibit bile salt hydrolase (BSH) activity in Clostridium perfringens.
Properties of 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine amidohydrolase
| storage temp. | -20°C |
| form | lyophilized powder |
Safety information for 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine amidohydrolase
Computed Descriptors for 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oylglycine amidohydrolase
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