3,5-Dichlorophenol
- CAS NO.：591-35-5
- Empirical Formula: C6H4Cl2O
- Molecular Weight: 163
- MDL number: MFCD00002259
- EINECS: 209-714-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:25
What is 3,5-Dichlorophenol?
Chemical properties
yellow to light brown crystals, crystalline powder
The Uses of 3,5-Dichlorophenol
3,5-Dichlorophenol is used as pharmaceutical intermediate.
Definition
ChEBI: 3,5-dichlorophenol is a dichlorophenol in which the two chloro substituents are located at positions 3 and 5.
What are the applications of Application
3,5-Dichlorophenol is a metabolite of the pesticides polychlorinated phenols and benzene hexachloride. found in chlorinated waste water; Used as a research chemical.
Preparation
Catalytic hydrodechlorination of polychlorophenols in organic or aqueous media with a palladium catalyst was used to obtain 3-chlorophenol and 3,5-dichlorophenol.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 4565, 1984 DOI: 10.1016/S0040-4039(01)81494-5
General Description
Prisms (from petroleum ether) or pink crystals.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
3,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.
Fire Hazard
Flash point data for 3,5-Dichlorophenol are not available. 3,5-Dichlorophenol is probably combustible.
Purification Methods
Crystallise 3,5-dichlorophenol from pet ether/*benzene mixture and/or distil it. [Beilstein 6 IV 957.]
Properties of 3,5-Dichlorophenol
| Melting point: | 65-68 °C (lit.) |
| Boiling point: | 233 °C (lit.) |
| Density | 1.3446 (rough estimate) |
| refractive index | 1.4430 (estimate) |
| Flash point: | 233°C |
| storage temp. | room temp |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | pKa 8.48(H2O t=25 I=0.025) (Uncertain) |
| form | Crystals, Crystalline Powder or Crystalline Mass |
| color | Yellow to light brown |
| Water Solubility | Slightly soluble in water. Very soluble in ethanol, ethyl ether and petroleum ether. |
| BRN | 1906458 |
| CAS DataBase Reference | 591-35-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 3,5-dichloro-(591-35-5) |
| EPA Substance Registry System | 3,5-Dichlorophenol (591-35-5) |
Safety information for 3,5-Dichlorophenol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H311:Acute toxicity,dermal H314:Skin corrosion/irritation H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,5-Dichlorophenol
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
You may like
-
591-35-5 3,5-Dichlorophenol 98%View Details
591-35-5 -
3,5-Dichlorophenol CAS 591-35-5View Details
591-35-5 -
3,5-Dichlorophenol CAS 591-35-5View Details
591-35-5 -
Crystals 3-5-Dichlorophenol CAS: 591-35-5, For CommericalView Details
591-35-5 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
68208-21-9 98+View Details
68208-21-9 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4 98+View Details
68208-18-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.