2,3-Dichlorophenol
Synonym(s):2,3-Dichlorophenol
- CAS NO.：576-24-9
- Empirical Formula: C6H4Cl2O
- Molecular Weight: 163
- MDL number: MFCD00002160
- EINECS: 209-399-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:28
What is 2,3-Dichlorophenol?
Chemical properties
2,3-dichlorophenol appears as light brown crystalline solid. Soluble in ether, chloroform and hot ethanol, insoluble in water and benzene.
The Uses of 2,3-Dichlorophenol
2,3-Dichlorophenol is a chemical reagent used in the synthesis of a small molecule IL-2 inhibitor.
Preparation
2,3-Dichlorophenol is obtained from 1,2,3-trichlorobenzene by sulfonation to salt and high pressure hydrolysis to 3,4-dichloro-2-hydroxybenzenesulfonic acid, then hydrolyzed by sulfuric acid to remove the sulfonic acid group.
General Description
Brown crystals (from ligroin, benzene). Taste threshold concentration 0.00004 mg/L. Odor threshold concentration 0.03 mg/L.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2,3-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.
Fire Hazard
Flash point data for 2,3-Dichlorophenol are not available. 2,3-Dichlorophenol is probably combustible.
Purification Methods
Crystallise it from ether. [Beilstein 6 IV 883.]
Properties of 2,3-Dichlorophenol
| Melting point: | 56 °C |
| Boiling point: | 214 °C |
| Density | 1.40 g/cm3 (25℃) |
| refractive index | 1.4430 (estimate) |
| Flash point: | 115 °C |
| storage temp. | 0-6°C |
| solubility | 3600mg/l (experimental) |
| form | neat |
| pka | 7.44(at 25℃) |
| color | White to Light red to Green |
| Water Solubility | <0.1 g/100 mL at 20 ºC |
| BRN | 2043615 |
| Stability: | Stable. Incompatible with oxidizing agents, acid chlorides, acid anhydrides. |
| CAS DataBase Reference | 576-24-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 2,3-dichloro-(576-24-9) |
| EPA Substance Registry System | 2,3-Dichlorophenol (576-24-9) |
Safety information for 2,3-Dichlorophenol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2,3-Dichlorophenol
2,3-Dichlorophenol manufacturer
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product: 576-24-9 2,3-Dichlorophenol >99%
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