3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
- CAS NO.：5439-14-5
- Empirical Formula: C8H8N2O
- Molecular Weight: 148.16
- MDL number: MFCD00042798
- EINECS: 226-618-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 15:14:04
![3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE Structural](https://img.chemicalbook.in/CAS/GIF/5439-14-5.gif)
What is 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE?
Purification Methods
Dissolve it in CHCl3, filter, evaporate, then recrystallise the residue from EtOH/Me2CO (needles) which can be washed with Et2O and dried. It can also be recrystallised from CHCl3/pet ether or CHCl3/hexane. The hydrochloride has m 295-295o (dec, from EtOH or MeOH/Et2O), the hydrobromide has m 299-300o(dec) (from MeOH/Et2O) and the picrate has m 224-226o(corr), m 219-220o from EtOH. [Adams & Pachter J Am Chem Soc 74 4906 1952, Lappin J Org Chem 23 1358 1958, Hurd & Hayao J Am Chem Soc 77 115 1955, Beilstein 24 III/IV 299.]
Properties of 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
| Melting point: | 185-187 °C |
| Boiling point: | 271℃ |
| Density | 1.26 |
| Flash point: | 118℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 2.83±0.20(Predicted) |
| color | Light Yellow |
| BRN | 3667723 |
Safety information for 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
New Products
1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate (R)-1-Benzyl-3-pyrrolidinecarbonitrile Dorzolamide trans isomer Ritonavir - Impurity U Doultegravir isomer 1 N-Nitroso Dextromethorphan EP-A Dolutegravir Isopropyl Analogue (14R dextromethorphan) 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 4-Fluorothiophenol 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 4-Bromo Benzylcyanide 3-Hydroxypropionitrile 3,4 Dimethoxy Benzylcyanide valeronitrile 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
![7-CHLORO-4-METHYL-2-OXO-3,4-DIHYDRO-2 H-PYRIDO[1,2-A ]PYRIMIDINE-4-CARBOXYLIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure6/GIF/CB6309183.gif)
![4-METHYL-2-OXO-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDINE-4-CARBOXYLIC ACID](https://img.chemicalbook.in/CAS/GIF/359418-42-1.gif)
![2,4-DIOXO-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB7108473.gif)
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3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one CAS 5439-14-5View Details
5439-14-5 -
Clidinium Bromide Related Compound B 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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N-Nitroso Atenolol EP Impurity I 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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N-Nitroso Atenolol EP Impurity I 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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Clidinium Bromide Related Compound B 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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N-Nitroso Atenolol EP Impurity I 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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N-Nitraso Atenolol EP Impurity G 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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N-Nitroso Atenolol EP Impurity I 25 MG 50 MG 100 MG 250 MG EXTRAView Details
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