3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
- CAS NO.：5439-14-5
- Empirical Formula: C8H8N2O
- Molecular Weight: 148.16
- MDL number: MFCD00042798
- EINECS: 226-618-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:27:12
![3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE Structural](https://img.chemicalbook.in/CAS/GIF/5439-14-5.gif)
What is 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE?
Purification Methods
Dissolve it in CHCl3, filter, evaporate, then recrystallise the residue from EtOH/Me2CO (needles) which can be washed with Et2O and dried. It can also be recrystallised from CHCl3/pet ether or CHCl3/hexane. The hydrochloride has m 295-295o (dec, from EtOH or MeOH/Et2O), the hydrobromide has m 299-300o(dec) (from MeOH/Et2O) and the picrate has m 224-226o(corr), m 219-220o from EtOH. [Adams & Pachter J Am Chem Soc 74 4906 1952, Lappin J Org Chem 23 1358 1958, Hurd & Hayao J Am Chem Soc 77 115 1955, Beilstein 24 III/IV 299.]
Properties of 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
| Melting point: | 185-187 °C |
| Boiling point: | 271℃ |
| Density | 1.26 |
| Flash point: | 118℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 2.83±0.20(Predicted) |
| color | Light Yellow |
| BRN | 3667723 |
Safety information for 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
New Products
2-Bromo-4-hydroxypyridine Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Cis-Tosylate 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1-aminocyclobutanecarbonitrile hydrochloride AMINO-O-TOLYL-ACETIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 2-(2-Bromophenyl)ethanol Boc-D-Glu(OMe)-OMe 2,5 Dibromopyridine Ethyl 4-hydroxy-3-oxobutanoate Dimethyl (2S)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)pentanedioate 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![7-CHLORO-4-METHYL-2-OXO-3,4-DIHYDRO-2 H-PYRIDO[1,2-A ]PYRIMIDINE-4-CARBOXYLIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure6/GIF/CB6309183.gif)
![4-METHYL-2-OXO-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDINE-4-CARBOXYLIC ACID](https://img.chemicalbook.in/CAS/GIF/359418-42-1.gif)
![2,4-DIOXO-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBALDEHYDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB7108473.gif)
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