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HomeProduct name listClopidol

Clopidol

Synonym(s):3,5-Dichloro-2,6-dimethyl-4-pyridinol

  • CAS NO.:2971-90-6
  • Empirical Formula: C7H7Cl2NO
  • Molecular Weight: 192.04
  • MDL number: MFCD00867211
  • EINECS: 221-008-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
Clopidol Structural

What is Clopidol?

Description

Clopidol is a coccidiostat. It prevents mortality of chickens infected with the parasites E. tenella, E. necatrix, E. acervuline, E. mivati, E. brunetti, and E. maxima. It has antimalarial activity against P. berghei in mice and P. cynomologi in rhesus macaques. Clopidol is a potential contaminant in food poultry. Formulations containing clopidol have been used in the prevention of coccidiosis in chickens.

Description

The drug methylchlorpindol is used for the prevention of coccidiosis in poultry.

Chemical properties

Clopidol is a white to light brown powder.
Clopidol

The Uses of Clopidol

GABA Cl channel agonist, antiparasitic

The Uses of Clopidol

An antibiotic used in veterinary medicine as a coccidiostat in poultry. Showed low order of acute and chronic toxicity in animals.

The Uses of Clopidol

An antiprotozoal agent.

What are the applications of Application

Clopidol is an antiprotozoal agent

Definition

A penta-substituted pyridine derivative.

General Description

White to light-brown, crystalline solid. Mp: 320°C. Practically insoluble in water. Administered to poultry to prevent the growth of pathogenic parasites.

Reactivity Profile

Clopidol is a non-combustible as a solid, but dust may burn rapidly or explode when mixed with air and ignited.

Hazard

Toxic. Mutagenic effects. Questionable carcinogen. Clopyralid.

Contact allergens

This drug is used for the prevention of coccidiosis in poultry.

Safety Profile

A nuisance dust. When heated to decomposition it emits very toxic fumes of Cland NOx.

Potential Exposure

Those engaged in formulation, application or manufacture of this veterinary antibiotic. Used as a pharmaceutical and as feed and food additive

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with clopidolyou should be trained on its proper handling and storage.Store in tightly closed containers in a cool, well-ventilatedarea.

Shipping

UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Noncombustible solid, but dust may explode in cloud form. Contact with strong oxidizers may cause a fire or explosion hazard

Waste Disposal

Dispose of contents and container to an approved waste disposal plant. All federal, state, and local environmental regulations must be observed. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

Properties of Clopidol

Melting point: >320℃
Boiling point: 318.4±37.0 °C(Predicted)
Density  1.2494 (rough estimate)
refractive index  1.5500 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  Aqueous Base (Slightly), Methanol (Slightly, Heated)
form  neat
pka 5.50±0.33(Predicted)
form  Solid
color  White to Off-White
Water Solubility  40mg/L(temperature not stated)
Stability: Hygroscopic
CAS DataBase Reference 2971-90-6(CAS DataBase Reference)
EPA Substance Registry System Clopidol (2971-90-6)

Safety information for Clopidol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Clopidol

InChIKey QCMHHYSPKNVXLR-UHFFFAOYSA-N

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