3-Nitro-1,8-naphthalic anhydride
Synonym(s):3-Nitronaphthalene-1,8-dicarboxylic anhydride
- CAS NO.：3027-38-1
- Empirical Formula: C12H5NO5
- Molecular Weight: 243.17
- MDL number: MFCD00006926
- EINECS: 629-274-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:50:36
What is 3-Nitro-1,8-naphthalic anhydride?
Chemical properties
Light yellow to beige or light brown powder
The Uses of 3-Nitro-1,8-naphthalic anhydride
3-Nitro-1,8-naphthalic anhydride is a reagent used to synthesize a monoboronic acid fluorescent sensor that exhibits emission suitable for ratiometric testing and also displays sensitivity for glucose relative to fructose and galactose. 3-Nitro-1,8-naphthalic anhydride is also used as a starting reagent in the synthesis of 5-substituted naphthalimide derivatives which exhibit high anti-cancer activity.
Properties of 3-Nitro-1,8-naphthalic anhydride
| Melting point: | 247-249 °C (dec.) (lit.) |
| Boiling point: | 386.04°C (rough estimate) |
| Density | 1.4429 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Powder |
| color | Light yellow to beige or light brown |
| BRN | 23762 |
| CAS DataBase Reference | 3027-38-1(CAS DataBase Reference) |
Safety information for 3-Nitro-1,8-naphthalic anhydride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Nitro-1,8-naphthalic anhydride
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