3-Methylthiophene
- CAS NO.:616-44-4
- Empirical Formula: C5H6S
- Molecular Weight: 98.17
- MDL number: MFCD00005470
- EINECS: 210-482-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:30
What is 3-Methylthiophene?
Chemical properties
clear colorless to light yellow liquid
The Uses of 3-Methylthiophene
Thiophene, 2-methyIthiopheney and 3-methylthiophene act as inhibitors for the polymerization of trichloroethylene in a solvent used for the degreasing of iron and aluminum, said polymerization being catalyzed by contact of the solvent with the metals. Bonz, in 1885, reported the formation of a dichloroethylthiophene from chlorination of 2-ethylthiophene in the cold. Is Opolski studied the chlorination of 2- and 3-methylthiophenes, 2-ethyl- and 2-butylthiophene and reported constants for the monochloro derivatives. Voerman has chlorinated 3-methylthiophene in the side chain with phosphorus trichloride in the sunlight, but concurrent ring chlorination predominates. 3-Methylthiophene gives a unique reaction with alkyl- or arylsodium in which the substitution takes place exclusively in the 5-position rather than in the expected 2-position.
The Uses of 3-Methylthiophene
A thiophene derivative used as an electropolymerization monomer in conducting polymer research.
The Uses of 3-Methylthiophene
Conducting polymer precursor.1
The Uses of 3-Methylthiophene
3-Methylthiophene is found in coffee and coffee products. it is a maillard product, present in roast coffee aroma.
3-Methylthiophene is a member of thiophenes. Conducting polymer precursor. Copolymerization of 3-alkylthiophene and 3-methylthiophene is a promising approach to provide a polymer which has both solution processible property and high electrical conductivity.
Definition
ChEBI: 3-Methylthiophene is a member of thiophenes.
Purification Methods
Dry it with Na2SO4, then distil it from sodium. [Beilstein 17 III/IV 277, 17/1 V 331.]
Properties of 3-Methylthiophene
| Melting point: | -69 °C (lit.) |
| Boiling point: | 114 °C/738 mmHg (lit.) |
| Density | 1.016 g/mL at 25 °C (lit.) |
| vapor pressure | 42.4 mm Hg ( 37.7 °C) |
| refractive index | n |
| Flash point: | 52 °F |
| storage temp. | Flammables area |
| solubility | 0.40g/l |
| form | Liquid |
| color | Clear colorless to light yellow |
| Specific Gravity | 1.016 |
| Water Solubility | insoluble |
| BRN | 1300 |
| Stability: | Volatile |
| CAS DataBase Reference | 616-44-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiophene, 3-methyl-(616-44-4) |
| EPA Substance Registry System | Thiophene, 3-methyl- (616-44-4) |
Safety information for 3-Methylthiophene
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 |
| GHS Hazard Statements |
H225:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. |
Computed Descriptors for 3-Methylthiophene
| InChIKey | QENGPZGAWFQWCZ-UHFFFAOYSA-N |
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran








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