3-Chloropropanesulfonyl chloride

CAS NO.：1633-82-5
Empirical Formula: C3H6Cl2O2S
Molecular Weight: 177.05
MDL number: MFCD00007463
EINECS: 216-646-3
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:57:56

What is 3-Chloropropanesulfonyl chloride?

Chemical properties

clear colorless to light brown liquid

The Uses of 3-Chloropropanesulfonyl chloride

3-Chloropropanesulfonyl chloride is an intermediate used in the preparation of many enzymatic inhibitors

The Uses of 3-Chloropropanesulfonyl chloride

Generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams1 and sultones.2

The Uses of 3-Chloropropanesulfonyl chloride

3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.

What are the applications of Application

3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors

Properties of 3-Chloropropanesulfonyl chloride

Boiling point:	70 °C/0.5 mmHg (lit.)
Density	1.456 g/mL at 25 °C (lit.)
refractive index	n20/D 1.489(lit.)
Flash point:	>230 °F
storage temp.	2-8°C
solubility	Soluble in dichloromethane, ethyl Acetate and hexane.
form	Liquid
color	Clear colorless to light brown
Sensitive	Lachrymatory
BRN	1754119
CAS DataBase Reference	1633-82-5(CAS DataBase Reference)

Safety information for 3-Chloropropanesulfonyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.