3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE
Synonym(s):3-(Trimethylsilyl)propargyl bromide;3-Bromo-1-(trimethylsilyl)-1-propyne
- CAS NO.：38002-45-8
- Empirical Formula: C6H11BrSi
- Molecular Weight: 191.14
- MDL number: MFCD00134460
- EINECS: 609-506-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:10:37
What is 3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE?
Chemical properties
Clear colorless to pale yellow liquid
The Uses of 3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE
3-Bromo-1-(trimethylsilyl)-1-propyne may be used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It may be used as reagent for the alkylation of dianion of β-keto esters at γ-carbon. It may be employed in the preparation of terminal conjugated enynes and allenic alcohols.
General Description
3-Bromo-1-(trimethylsilyl)-1-propyne is reported as a propargylating agent. Selective reaction of 3-bromo-1-(trimethylsilyl)-1-propyne with α-keto ester using indium metal has been studied.
Properties of 3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE
| Melting point: | <0°C |
| Boiling point: | 44-45 °C2 mm Hg(lit.) |
| Density | 1.17 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 145 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Colourless to Pale Yellow |
| Specific Gravity | 1.351 |
| Water Solubility | Immiscible with water. |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| BRN | 2037650 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 38002-45-8(CAS DataBase Reference) |
Safety information for 3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE
| InChIKey | GAPRPFRDVCCCHR-UHFFFAOYSA-N |
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
3-Bromo-1-(trimethylsilyl)-1-propyne CAS 38002-45-8View Details
38002-45-8 -
3-Bromo-1-(trimethylsilyl)-1-propyne CAS 38002-45-8View Details
38002-45-8 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO25View Details -
DGO29View Details -
DGO32View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.