2,6-Diisopropylaniline
- CAS NO.:24544-04-5
- Empirical Formula: C12H19N
- Molecular Weight: 177.29
- MDL number: MFCD00008887
- EINECS: 246-305-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-11-25 16:17:10
What is 2,6-Diisopropylaniline?
Chemical properties
Clear liquid
The Uses of 2,6-Diisopropylaniline
2,6-Diisopropylaniline acts as an intermediate used in the production of carbodiimides stabilizers, synthetic resins, antioxidants and active pharmaceutical ingredients. It is also used in the preparation of multitopic Schiff-base ligand precursors and 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene. It also undergoes condensation reaction with triacetylmethane to get -[1-(2,6-diisopropylphenylamino)ethylidene]pentane-2,4-dione. Further, it is used to prepare N-heterocyclic carbene complexes for alfa-arylation of acyclic ketones, amination of haloarenes and aqueous Suzuki coupling. In addition to this, it is used in the prepartion of organocatalyst based on naphthalene diimides.
The Uses of 2,6-Diisopropylaniline
2,6-Diisopropylaniline is used as intermediate for the manufacture of carbodiimides stabilizers, RIM-PUR, synthetic resins, pesticides, antioxidants, pharmaceuticals and other products.
2,6-Diisopropylaniline may be used in the preparation of multitopic Schiff-base ligand precursors.It may be used in the preparation of NSN-donor proligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene. It may be used to prepare N-heterocyclic carbene complexes for α-arylation of acyclic ketones, amination of haloarenes, and aqueous Suzuki coupling.
2,6-Diisopropylaniline may be used in the preparation of organocatalyst based on naphthalene diimides (NDIs).
The Uses of 2,6-Diisopropylaniline
2,6-Diisopropylaniline was used in the preparation of multitopic Schiff-base ligand precursors. It was also used in the preparation of NSN-donor proligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene.
Reactions
2,6-Diisopropylaniline is an amine. It undergoes condensation with triacetylmethane in toluene in the presence of p-toluenesulfonic acid provides 3-[1-(2,6-diisopropylphenylamino)ethylidene]pentane-2,4-dione. 2,6-Diisopropylaniline is an aromatic amine. It reacts with bis(trimethylsilylmethyl)yttrium complexes supported by bulky amidopyridinate (Ap) and amidinate (Amd) ligands to afford yttrium alkyl anilido species. This reaction involves the elimination of TMS (Trimethylsilane).
General Description
2,6-Diisopropylaniline is an aromatic amine. It reacts with bis(trimethylsilylmethyl)yttrium complexes supported by bulky amidopyridinate (Ap) and amidinate (Amd) ligands to afford yttrium alkyl anilido species. This reaction involves the elimination of TMS (Trimethylsilane).
Properties of 2,6-Diisopropylaniline
| Melting point: | -45 °C (lit.) |
| Boiling point: | 257 °C (lit.) |
| Density | 0.94 g/mL at 25 °C (lit.) |
| vapor pressure | <0.01 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | 255 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | <0.2g/l |
| form | Liquid |
| pka | 4.25±0.10(Predicted) |
| color | Clear |
| Water Solubility | <0.20 g/L |
| BRN | 2208763 |
| CAS DataBase Reference | 24544-04-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenamine, 2,6-bis(1-methylethyl)-(24544-04-5) |
| EPA Substance Registry System | 2,6-Diisopropylaniline (24544-04-5) |
Safety information for 2,6-Diisopropylaniline
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,6-Diisopropylaniline
| InChIKey | WKBALTUBRZPIPZ-UHFFFAOYSA-N |
New Products
4-Bromo-2-chlorobenzonitrile 1-Chloro-4-Methyl-2-Nitrobenzene 1,3-Diethyl-1,3-Diphenylurea 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile Vitamin D3 vegan Progesterone Boldenone Clarithromycin Ethinyl Estradiol Stanozolol 2-Nitroacetophenone Methyl 2-oxo-2,3-dihydrobenzo[d]oxazole-7-carboxylate 4-(2-Aminoethyl)-7-hydroxy-2H-chromoen-2-one 3-Hydroxy-4-nitrobromobenzene 2-Ethyl-1,4-diaminobenzene 2-Ethylhexyl 4-aminobenzoate Thio AcetamideRelated products of tetrahydrofuran








You may like
-
2,6-Diisopropylaniline CAS 24544-04-5View Details
24544-04-5 -
2,6-Diisopropylaniline, 97% CAS 24544-04-5View Details
24544-04-5 -
2,6-Diisopropylaniline CAS 24544-04-5View Details
24544-04-5 -
2,6-Diisopropylaniline CAS 24544-04-5View Details
24544-04-5 -
2,6-Diisopropylaniline CAS 24544-04-5View Details
24544-04-5 -
Trenbolone Enanthate 98%View Details
1629618-98-9 -
121-54-0 Benzethonium Chloride 98%View Details
121-54-0 -
Testosterone acetate 1045-69-8 98%View Details
1045-69-8

