N,N-Diisopropylethylamine
Synonym(s):DIPEA;N,N-Diisopropylethylamine;Ethyldiisopropylamine;N-Ethyldiisopropylamine;Hünig’s base
- CAS NO.:7087-68-5
- Empirical Formula: C8H19N
- Molecular Weight: 129.24
- MDL number: MFCD00008868
- EINECS: 230-392-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-17 13:57:11
What is N,N-Diisopropylethylamine?
Description
DIEA is a base that is widely used in organic synthesis. The three relatively bulky alkyl groups attached to the nitrogen make DIEA a non-nucleophilic base.
The Uses of N,N-Diisopropylethylamine
N,N-Diisopropylethylamine is used as a base in organic reactions. Used in the preparation of (-)Gambierol a marine polycyclic ether toxin. It is also used in the synthesis of potent inhibitors of human brain memapsin, a key effector in the progression of Alzheimer’s disease.
Properties of N,N-Diisopropylethylamine
Melting point: | <-50 °C (lit.) |
Boiling point: | 127 °C (lit.) |
Density | 0.742 g/mL at 25 °C (lit.) |
Flash point: | 6 °C |
storage temp. | Store below +30°C. |
solubility | miscible |
form | Liquid |
appearance | Colorless liquid |
color | APHA: <20 |
Water Solubility | miscible |
Safety information for N,N-Diisopropylethylamine
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Environment GHS09 |
GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H318:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N,N-Diisopropylethylamine
InChIKey | JGFZNNIVVJXRND-UHFFFAOYSA-N |
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