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HomeProduct name listN,N-Diisopropylethylamine

N,N-Diisopropylethylamine

Synonym(s):DIPEA;N,N-Diisopropylethylamine;Ethyldiisopropylamine;N-Ethyldiisopropylamine;Hünig’s base

  • CAS NO.:7087-68-5
  • Empirical Formula: C8H19N
  • Molecular Weight: 129.24
  • MDL number: MFCD00008868
  • EINECS: 230-392-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-17 13:57:11
N,N-Diisopropylethylamine Structural Picture

What is N,N-Diisopropylethylamine?

Description

DIEA is a base that is widely used in organic synthesis. The three relatively bulky alkyl groups attached to the nitrogen make DIEA a non-nucleophilic base.

The Uses of N,N-Diisopropylethylamine

N,N-Diisopropylethylamine is used as a base in organic reactions. Used in the preparation of (-)Gambierol a marine polycyclic ether toxin. It is also used in the synthesis of potent inhibitors of human brain memapsin, a key effector in the progression of Alzheimer’s disease.

Properties of N,N-Diisopropylethylamine

Melting point: <-50 °C (lit.)
Boiling point: 127 °C (lit.)
Density  0.742 g/mL at 25 °C (lit.)
Flash point: 6 °C
storage temp.  Store below +30°C.
solubility  miscible
form  Liquid
appearance Colorless liquid
color  APHA: <20
Water Solubility  miscible

Safety information for N,N-Diisopropylethylamine

Signal word Danger
Pictogram(s)

Flame
Flammables
GHS02

Corrosion
Corrosives
GHS05

Skull and Crossbones
Acute Toxicity
GHS06

Environment
GHS09
GHS Hazard Statements H225:Flammable liquids
H302:Acute toxicity,oral
H318:Serious eye damage/eye irritation
H331:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N,N-Diisopropylethylamine

InChIKey JGFZNNIVVJXRND-UHFFFAOYSA-N

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