2,5-Dimethylthiophene
Synonym(s):NSC 60689
- CAS NO.：638-02-8
- Empirical Formula: C6H8S
- Molecular Weight: 112.19
- MDL number: MFCD00005452
- EINECS: 211-313-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:22
What is 2,5-Dimethylthiophene?
Chemical properties
clear colorless to slightly yellow liquid
The Uses of 2,5-Dimethylthiophene
2,5-Dimethylthiophene is used as an intermediate in organic synthesis.
Definition
ChEBI: 2,5-Dimethylthiophene is a member of thiophenes.
Synthesis Reference(s)
The Journal of Organic Chemistry, 20, p. 1363, 1955 DOI: 10.1021/jo01127a012
General Description
2,5-Dimethylthiophene is a volatile flavoring compound that has been identified in the essential oil of onion. It is reported to be one of the sulfur-containing compounds formed via Maillard reaction/Strecker degradation of cysteine with furaneol.
Properties of 2,5-Dimethylthiophene
| Melting point: | -63°C |
| Boiling point: | 134 °C/740 mmHg (lit.) |
| Density | 0.985 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 75 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 0.985 |
| Odor | at 0.10 % in propylene glycol. nutty sulfury |
| Water Solubility | Insoluble in water. Soluble in alcohol, ether and benzene. |
| BRN | 106450 |
| CAS DataBase Reference | 638-02-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiophene, 2,5-dimethyl-(638-02-8) |
| EPA Substance Registry System | 2,5-Dimethylthiophene (638-02-8) |
Safety information for 2,5-Dimethylthiophene
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for 2,5-Dimethylthiophene
| InChIKey | GWQOOADXMVQEFT-UHFFFAOYSA-N |
2,5-Dimethylthiophene manufacturer
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