2,5-Dimethylpyridine
Synonym(s):2,5-Dimethylpyridine
- CAS NO.：589-93-5
- Empirical Formula: C7H9N
- Molecular Weight: 107.15
- MDL number: MFCD00006343
- EINECS: 209-666-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:44
What is 2,5-Dimethylpyridine?
The Uses of 2,5-Dimethylpyridine
2,5-Lutidine was used to displace CO from the haem iron.
Synthesis Reference(s)
Tetrahedron Letters, 17, p. 383, 1976 DOI: 10.1016/S0040-4039(00)93738-9
General Description
The FT-IR and FT-Raman spectra of 2,5-lutidine was studied.
Purification Methods
Steam distil the lutidine from a solution containing 1-2 equivalents of 20% H2SO4 until about 10% of the base has been carried over with the non-basic impurities, then the acidic solution is made alkaline, and the base is separated, dried with NaOH and fractionally distilled twice. Dry the distillate with Na and fractionally distil it through a Todd column (p 11) packed with glass helices. The hydrochloride has m 219o(dec), and the picrate has m 170.5o (from EtOH or H2O). [Beilstein 20 H 244, 20 II 160, 20 III/IV 2774, 20/6 V 27.]
Properties of 2,5-Dimethylpyridine
| Melting point: | −15 °C(lit.) |
| Boiling point: | 157 °C(lit.) |
| Density | 0.926 g/mL at 25 °C(lit.) |
| vapor pressure | 2.4 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | 118 °F |
| form | clear liquid |
| pka | 6.4(at 25℃) |
| color | Colorless to Light orange to Yellow |
| Water Solubility | 77g/L(23 ºC) |
| Sensitive | Hygroscopic |
| CAS DataBase Reference | 589-93-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyridine, 2,5-dimethyl-(589-93-5) |
| EPA Substance Registry System | 2,5-Dimethylpyridine (589-93-5) |
Safety information for 2,5-Dimethylpyridine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,5-Dimethylpyridine
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