25-DESACETYL RIFAMPICIN
- CAS NO.：16783-99-6
- Empirical Formula: C41H56N4O11
- Molecular Weight: 780.9
- MDL number: MFCD08063717
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 22:16:43
What is 25-DESACETYL RIFAMPICIN?
Description
25-desacetyl rifampicin, also known as 25-deacetyl-rifampicin, is the main metabolite of rifampicin. It has partial activity. Rifampicin mainly treats various forms of tuberculosis. High-Performance Liquid Chromatographic can be used to determine the metabolism of rifampicin in the body by checking the concentration of 25-desacetyl rifampicin in the urine or blood of tuberculosis patients[1-3].
Chemical properties
Dark Red Solid
The Uses of 25-DESACETYL RIFAMPICIN
A metabolite of Rifampicin.
What are the applications of Application
25-Desacetyl Rifampicin is a metabolite of Rifampicin
References
[1]Chik Z, et al. A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers. Clinical Therapeutics, 2011.
[2] Mohan B, et al.Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. Journal of Pharmaceutical and Biomedical Analysis, 2003; 31: 607-612.
[3] Lily, et al. The influence of mutation gene rpoB of Mycobacterium tuberculosis cluster I (507-534) on the elimination 25-desacetyl rifampicin in urine of tuberculosis subjects. IOP Conference Series: Earth and Environmental Science, 2018; 1755-1315.
Properties of 25-DESACETYL RIFAMPICIN
| Melting point: | >300°C |
| Boiling point: | 943.1±65.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.96±0.70(Predicted) |
| color | Dark Red to Black |
| Stability: | Light Sensitive |
Safety information for 25-DESACETYL RIFAMPICIN
Computed Descriptors for 25-DESACETYL RIFAMPICIN
| InChIKey | KUJZTIJOBQNKDR-ACYBWPGYNA-N |
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![RIFAMPIN, [4-METHYLPIPERAZINE-3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB5671638.gif)
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