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HomeProduct name list2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Structural

What is 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE?

Description

Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 μM independent of MAO-A activity.

The Uses of 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

Antidepressive;Monoamine oxidase inhibitor

What are the applications of Application

Pirlindole mesylate is an inhibitor of monoamine oxidase type A

Biological Activity

A highly selective reversible inhibitor of monoamine oxidase type A.

Properties of 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

storage temp.  Store at RT
solubility  DMF: 1 mg/ml; DMSO: 5 mg/ml
form  A crystalline solid
color  Off-white to light yellow

Safety information for 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

Computed Descriptors for 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

New Products

DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioate

Related products of tetrahydrofuran

8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-3H-PYRAZINO[3,2,1-JK]CARBAZOLE-3-CARBALDEHYDE
8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-3H-PYRAZINO[3,2,1-JK]CARBAZOLE-3-CARBALDEHYDE
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
3-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO-[3,2,1-JK]CARBAZOL-3-YL)PROPIONIC ACID
3-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO-[3,2,1-JK]CARBAZOL-3-YL)PROPIONIC ACID
2,3,3A,4,5,6-HEXAHYDRO-8-CYCLOHEXYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
2,3,3A,4,5,6-HEXAHYDRO-8-CYCLOHEXYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
2-CHLORO-1-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO[3,2,1-JK]CARBAZOL-3-YL)-ETHANONE
2-CHLORO-1-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO[3,2,1-JK]CARBAZOL-3-YL)-ETHANONE
3-BENZYL-2,3,3A,4,5,6-HEXAHYDRO-1H-PYRAZINO[3,2,1-JK]CARBAZOLE-8-CARBALDEHYDE
3-BENZYL-2,3,3A,4,5,6-HEXAHYDRO-1H-PYRAZINO[3,2,1-JK]CARBAZOLE-8-CARBALDEHYDE
10-CYCLOHEXYL-1,2,3,3A,4,5-HEXAHYDRO-6H-PYRAZINO[1,2,3-L,M]CARBAZOLE
10-CYCLOHEXYL-1,2,3,3A,4,5-HEXAHYDRO-6H-PYRAZINO[1,2,3-L,M]CARBAZOLE
1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-3-prop yl-, hydrochloride
1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-3-prop yl-, hydrochloride

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