2',3'-DIDEOXY-3'-FLUOROURIDINE
Synonym(s):3′-Fluoro-2′,3′-dideoxyuridine
- CAS NO.:41107-56-6
- Empirical Formula: C9H11FN2O4
- Molecular Weight: 230.19
- MDL number: MFCD00192015
- EINECS: 415-360-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 2',3'-DIDEOXY-3'-FLUOROURIDINE?
Chemical properties
Off-white solid
The Uses of 2',3'-DIDEOXY-3'-FLUOROURIDINE
2'',3''-Dideoxy-3''-fluorouridine is a reactant used in the synthesis of 5''-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.
The Uses of 2',3'-DIDEOXY-3'-FLUOROURIDINE
2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:
- 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
- 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.
What are the applications of Application
2′,3′-Dideoxy-3′-fluorouridine is an anti-retroviral compound
General Description
2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.
Properties of 2',3'-DIDEOXY-3'-FLUOROURIDINE
| Melting point: | 184-188 °C(lit.) |
| Density | 1.50±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Water |
| pka | 9.39±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]20/D +10.5°, c = 0.5 in 1 M NaOH |
| BRN | 6064366 |
Safety information for 2',3'-DIDEOXY-3'-FLUOROURIDINE
| Signal word | Warning |
| Pictogram(s) |
![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P281:Use personal protective equipment as required. |
Computed Descriptors for 2',3'-DIDEOXY-3'-FLUOROURIDINE
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