2,2,6,6-Tetramethyl-4-piperidone hydrochloride
- CAS NO.：33973-59-0
- Empirical Formula: C9H18ClNO
- Molecular Weight: 191.7
- MDL number: MFCD00012768
- EINECS: 251-769-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is 2,2,6,6-Tetramethyl-4-piperidone hydrochloride?
Chemical properties
white to slightly beige crystalline powder
The Uses of 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
2,2,6,6-Tetramethyl-4-piperidone hydrochloride has been used as a reagent injected in the micromixer using a Rheodyne injection valve for introducing discrete sample pulses into the miniaturised-SYNthesis and Total Analysis System (πSYNTAS).
Purification Methods
Purify the salt by recrystallisation from EtOH/Et2O, MeCN or Me2CO/MeOH. The free base has m 37-39o (after sublimation), b 102-105o/18mm, and the hydrate has m 56-58o (wet Et2O); the hydrobromide has m 203o (from EtOH/Et2O), and the picrate has m 196o (from aqueous EtOH). [Sandris & Ourisson Bull Soc Chim Fr 345 1958, Beilstein 21 H 246, 21 I 273, 21 II 222, 21 III/IV 3278, 21/6 V 538.]
Properties of 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
| Melting point: | 198 °C (dec.)(lit.) |
| storage temp. | Sealed in dry,Room Temperature |
| color | White to off-white |
| BRN | 4154554 |
| CAS DataBase Reference | 33973-59-0(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride (33973-59-0) |
Safety information for 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
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