2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE
- CAS NO.：4158-86-5
- Empirical Formula: C5H8O3
- Molecular Weight: 116.12
- MDL number: MFCD03093984
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 17:20:54
What is 2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE?
The Uses of 2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE
2,2-Dimethyl-1,3-dioxolan-4-one (cas# 4158-86-5) is a compound useful in organic synthesis.
The Uses of 2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE
2,2-Dimethyl-1,3-dioxolan-4-one may be used in the synthesis of the following N,N-disubstituted amides of glycolic acid:
- N,N-diethyl-2-hydroxyacetamide
- N,N-di(n-butyl)-2-hydroxyacetamide
- N,N-di(n-hexyl)-2-hydroxyacetamide
- 4-hydroxyacetylpiperidine
- 4-hydroxyacetylmorpholine
- N-ethyl-N-phenyl-2-hydroxyacetamide
General Description
2,2-Dimethyl-1,3-dioxolan-4-one can be prepared via condensation reaction between glycolic acid and acetone in the presence of P2O5 in diethyl ether.
Properties of 2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE
| Boiling point: | 41 °C (lit.) |
| Density | 0.989 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 135 °F |
Safety information for 2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2-DIMETHYL-1,3-DIOXOLAN-4-ONE
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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