20-HETE
Synonym(s):20-HETE;20-Hydroxyarachidonic acid
- CAS NO.：79551-86-3
- Empirical Formula: C20H32O3
- Molecular Weight: 320.47
- MDL number: MFCD00171542
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-28 17:32:21
What is 20-HETE?
The Uses of 20-HETE
20-HETE is a cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature.
Definition
ChEBI: A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20.
Biochem/physiol Actions
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid (20-HETE) is an arachidonic acid metabolite via cytochrome P4504A, that is an activator of the Ras/MAP (microtubule-associated protein) pathway. 20-HETE acid is a predominant arachidonic acid present in the kidney. It is involved in the regulation of sodium, potassium and chloride transport in the renal tubules. 20-HETE is often excreted in urine in the form of glucuronide conjugate and sometimes as free acids. Increased urine 20-HETE is observed during pregnancy in rats.
Properties of 20-HETE
| Boiling point: | 482.0±33.0 °C(Predicted) |
| Density | 0.985±0.06 g/cm3(Predicted) |
| Flash point: | 14℃ |
| storage temp. | -20°C |
| solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
| form | Powder |
| pka | 4.75±0.10(Predicted) |
Safety information for 20-HETE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 20-HETE
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 4-(4-Αminophenyl)-3-Morpholinone 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one N-cyanoacetylurethane 1H-IndazoleRelated products of tetrahydrofuran
You may like
-
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid CAS 79551-86-3View Details
79551-86-3 -
471-25-0 Propiolic Acid 98+View Details
471-25-0 -
84145-28-8 98+View Details
84145-28-8 -
trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 98+View Details
63909-29-5 -
2-(2-Chlorophenyl)glycine 88744-36-9 98+View Details
88744-36-9 -
40216-83-9 trans-4-Hydroxy-L-proline methyl ester hydrochloride 98+View Details
40216-83-9 -
629-76-5 98+View Details
629-76-5 -
1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene 98+View Details
39816-35-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.