2-Pyridinol-1-oxide
Synonym(s):1-Hydroxy-2-pyridone;2-Hydroxypyridine 1-oxide;HOPO
- CAS NO.：13161-30-3
- Empirical Formula: C5H5NO2
- Molecular Weight: 111.1
- MDL number: MFCD00006195
- EINECS: 236-100-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 2-Pyridinol-1-oxide?
Chemical properties
Weight 20% solution in water
The Uses of 2-Pyridinol-1-oxide
2-Pyridinol 1-oxide can be used:????
- To fabricate gold electrodes for the electrochemical determination of europium using cyclic voltammetry.????????
- To prepare polymeric nickel (II) complex of 2-hydroxypyridine-N-oxide.
- In the synthesis of 1-methoxypyrid-4-one in the presence of sodium methoxide and methyl toluene-9-sulphonate.
What are the applications of Application
2-Pyridinol 1-oxide is A peptide coupling agent
Definition
Bactericidal agent related to aspergillic acid, made from pyridine-N-oxide.
General Description
2-Pyridinol 1-oxide (HOPO) is a peptide coupling agent used as a subsititue for HOBt. It can form stable chelate complexes with transition metal ions.
Properties of 2-Pyridinol-1-oxide
| Melting point: | 147-152 °C |
| Boiling point: | 387.7±15.0 °C(Predicted) |
| Density | 1.111 |
| vapor pressure | 0.223Pa at 25℃ |
| Flash point: | 100 °C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | pK1:-0.62;pK2:5.97(0) (25°C) |
| color | Off-White to Light Yellow |
| Water Solubility | 331g/L |
| BRN | 1422545 |
| CAS DataBase Reference | 13161-30-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinol-1-oxide(13161-30-3) |
Safety information for 2-Pyridinol-1-oxide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Pyridinol-1-oxide
| InChIKey | JVHZMYAXZUIZKS-UHFFFAOYSA-N |
2-Pyridinol-1-oxide manufacturer
JSK Chemicals
2Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 13161-30-3 2-Pyridinol 1-oxide, 98% 99%
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 2-Hydroxypyridine -N-oxide 13161-30-3 98%
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