2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
- CAS NO.：123875-01-4
- Empirical Formula: C19H23NO4S
- Molecular Weight: 361.46
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 22:16:43
What is 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate?
The Uses of 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
PCA 4248 is a competitive inhibitor of PAF at the PAF-R level.
What are the applications of Application
PCA 4248 is a competitive inhibitor of PAF at the PAF-R level
Definition
ChEBI: 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-[2-(phenylthio)ethyl] ester is a dihydropyridine.
Biological Activity
A specific PAF antagonist, more potent than the ginkolide BN-52021. Inhibits rabbit platelet aggregation with an IC 50 value of 1.05 μ M and has no significant activity on Ca 2+ channels. Active in vivo , antagonising PAF-induced systemic hypotension and protein-plasma extravasation in rats.
Properties of 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
| storage temp. | Desiccate at -20°C |
| solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| form | Powder |
Safety information for 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
Computed Descriptors for 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
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