2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Synonym(s):N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine;2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine;Comins’ Reagent
- CAS NO.:145100-51-2
- Empirical Formula: C7H3ClF6N2O4S2
- Molecular Weight: 392.68
- MDL number: MFCD00191833
- EINECS: 629-110-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-10-31 16:47:27
What is 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE?
The Uses of 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.
Properties of 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Melting point: | 45-47 °C(lit.) |
Boiling point: | 77-90°C/0.2mmHg |
Density | 1.892±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Benzene (Slightly) |
form | Solid |
color | yellow |
Water Solubility | Reacts with water. |
Sensitive | Moisture Sensitive |
Safety information for 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
InChIKey | TUFGVZMNGTYAQD-UHFFFAOYSA-N |
Abamectin manufacturer
ALS INDIA LIFE SCIENCES
1Y
Phone:+91-8977036379
Whatsapp: +91 8008166674
product: 145100-51-2 Comins' reagent 98%
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 3-NITRO-5-ACETYL IMINODIBENZYL 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THF 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE)Related products of tetrahydrofuran
Mesitylene-2-sulfonyl chloride
TRIFLUOROMETHANESULFONIMIDE
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
TRIFLUOROMETHANESULFONAMIDE
2-Amino-5-chloropyridine
2-[N,N-BIS(TRIFLUOROMETHYLSULFONYL)AMINO]PYRIDINE
You may like
-
145100-51-2 Comins' reagent 98%View Details
145100-51-2 -
2,3 Dichloro-4-Hydroxy Aniline 39183-17-0 99%View Details
39183-17-0 -
17673-56-2 99%View Details
17673-56-2 -
13463-67-7 Titanium Dioxide 99%View Details
13463-67-7 -
143-07-7 99%View Details
143-07-7 -
Ethanolamine 141-43-5 99%View Details
141-43-5 -
20776-67-4 99%View Details
20776-67-4 -
acid blue 113, acid navy blue , wool navy blue 0View Details
3351-05-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.