2-Methoxy-5-nitrobenzyl bromide
Synonym(s):2-Bromomethyl-4-nitroanisole;Koshland’s Reagent II
- CAS NO.：3913-23-3
- Empirical Formula: C8H8BrNO3
- Molecular Weight: 246.06
- MDL number: MFCD00007329
- EINECS: 223-471-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:10
What is 2-Methoxy-5-nitrobenzyl bromide?
The Uses of 2-Methoxy-5-nitrobenzyl bromide
2-Methoxy-5-nitrobenzyl bromide was used to modify tryptophan residues of mouse interferon to enhance their activity. It was also used as reagent for sulfhydryl modification.
General Description
2-Methoxy-5-nitrobenzyl bromide is a potential mechanism-based inactivator of enzymes that perform O-dealkylations.
Biochem/physiol Actions
2-Methoxy-5-nitrobenzyl bromide inactivates cytochrome P-450 in male rat liver microsomes.
Properties of 2-Methoxy-5-nitrobenzyl bromide
| Melting point: | 76-78 °C(lit.) |
| Boiling point: | 348.7±27.0 °C(Predicted) |
| Density | 1.589±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
Safety information for 2-Methoxy-5-nitrobenzyl bromide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methoxy-5-nitrobenzyl bromide
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