2-Hydrazino-4-(trifluoromethyl)pyrimidine
- CAS NO.：197305-97-8
- Empirical Formula: C5H5F3N4
- Molecular Weight: 178.12
- MDL number: MFCD00115112
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:26
What is 2-Hydrazino-4-(trifluoromethyl)pyrimidine?
Chemical properties
White to light yellow solid
The Uses of 2-Hydrazino-4-(trifluoromethyl)pyrimidine
2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used as a derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum. Synthesis of organohydrazide chelate complexes of rhenium and technetium. Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
The Uses of 2-Hydrazino-4-(trifluoromethyl)pyrimidine
2-Hydrazino-4-(trifluoromethyl)pyrimidine may be used in the following studies:
- As derivatization reagent for the simultaneous determination of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum samples by liquid chromatography-electrospray ionization-tandem mass spectrometry.
- Synthesis of organohydrazide chelate complexes of rhenium and technetium, having a metal-nitrogen-nitrogen linkage.
- Preparation of 1-(4-methoxyphenyl)ethanone [(4-trifluoromethyl)pyrimidine-2-yl]hydrazone (NAS-75).
Properties of 2-Hydrazino-4-(trifluoromethyl)pyrimidine
| Melting point: | 99-101 °C(lit.) |
| Boiling point: | 187.4±50.0 °C(Predicted) |
| Density | 1.62±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in aqueous acid. |
| form | powder to crystal |
| pka | 5.63±0.40(Predicted) |
| color | White to Orange to Green |
Safety information for 2-Hydrazino-4-(trifluoromethyl)pyrimidine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H302:Acute toxicity,oral H311:Acute toxicity,dermal H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Hydrazino-4-(trifluoromethyl)pyrimidine
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