2-(Fluorosulfonyl)difluoroacetic acid
Synonym(s):(Fluorosulfonyl)difluoroacetic acid
- CAS NO.：1717-59-5
- Empirical Formula: C2HF3O4S
- Molecular Weight: 178.09
- MDL number: MFCD01320807
- EINECS: 808-179-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:13:36
What is 2-(Fluorosulfonyl)difluoroacetic acid?
The Uses of 2-(Fluorosulfonyl)difluoroacetic acid
An important reagent in the synthesis of difluorocarbenes and difluorocyclopropanes.
The Uses of 2-(Fluorosulfonyl)difluoroacetic acid
Difluorocarbene source for the difluoromethylation of alcohols.
The Uses of 2-(Fluorosulfonyl)difluoroacetic acid
2,2-Difluoro-2-(fluorosulfonyl)acetic acid, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used as an important reagent in the synthesis of difluorocarbenes and difluorocyclopropanes.
General Description
2,2-Difluoro-2-(fluorosulfonyl)acetic acid reagent is employed as a difluorocarbene source for difluoromethylation of phenolic hydroxyl groups.
Properties of 2-(Fluorosulfonyl)difluoroacetic acid
| Boiling point: | 153 °C(lit.) |
| Density | 1.723 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| solubility | Chloroform (Soluble), DMSO (Slightly) |
| form | liquid |
| pka | -0.38±0.10(Predicted) |
| color | colorless |
| Water Solubility | It is soluble in water. |
| Sensitive | Moisture Sensitive |
| CAS DataBase Reference | 1717-59-5(CAS DataBase Reference) |
Safety information for 2-(Fluorosulfonyl)difluoroacetic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(Fluorosulfonyl)difluoroacetic acid
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