2-Ethylhexyl 4-hydroxybenzoate

CAS NO.：5153-25-3
Empirical Formula: C15H22O3
Molecular Weight: 250.33
MDL number: MFCD00016472
EINECS: 225-925-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-02 17:37:48

What is 2-Ethylhexyl 4-hydroxybenzoate?

Characteristics

The characteristics of 2-Ethylhexyl 4-hydroxybenzoate are: with the increase of the alkyl group in the paraben, the water solubility gradually decreases, the fat solubility increases gradually, the toxicity also decreases, and the antibacterial activity increases , in which esters of alkyl carbon chains with 11 and 12 carbons have the greatest antibacterial activity.

The Uses of 2-Ethylhexyl 4-hydroxybenzoate

2-Ethylhexyl 4-hydroxybenzoate is a broad-spectrum, high-efficiency, low-toxicity food preservative, and one of the three major food preservatives recognized internationally.

Definition

ChEBI: 2-Ethylhexyl-4-hydroxybenzoate is a benzoate ester.

Synthesis

Synthesis of 2-Ethylhexyl 4-hydroxybenzoate usually uses p-hydroxybenzoic acid (P-hydroxybenzoic acid) and the corresponding alcohol for esterification to azeotrope with water agents (such as petroleum ether, benzene, toluene, cyclohexane, etc.)

Properties of 2-Ethylhexyl 4-hydroxybenzoate

Boiling point:	270°C/50mmHg(lit.)
Density	1.035±0.06 g/cm3(Predicted)
refractive index	1.5190 to 1.5220
pka	8.20±0.15(Predicted)
form	clear liquid
color	Colorless to Light yellow to Light orange
CAS DataBase Reference	5153-25-3(CAS DataBase Reference)
EPA Substance Registry System	Benzoic acid, 4-hydroxy-, 2-ethylhexyl ester (5153-25-3)

Safety information for 2-Ethylhexyl 4-hydroxybenzoate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..…