2-Chloropyrazine
- CAS NO.：14508-49-7
- Empirical Formula: C4H3ClN2
- Molecular Weight: 114.53
- MDL number: MFCD00006124
- EINECS: 238-517-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-08-25 20:17:46
What is 2-Chloropyrazine?
Chemical properties
clear colorless to yellowish liquid
The Uses of 2-Chloropyrazine
2-Chloropyrazine is used in cardiotonic, in biological, drug, flavoring and perfumery industry.
What are the applications of Application
2-Chloropyrazine is used as a reagent in the synthesis of hetaryloxy benzoxaborole compounds which have antimalarial activity. 2-Chloropyrazine is also used to prepare 4,5-disubstituted 6-aryloxy-1,3-dihydrobenzo[c][1,2]oxaboroles which are broad-spectrum serine β-lactamase inhibitors.
Definition
ChEBI: 2-chloropyrazine is a member of pyrazines.
Purification Methods
Fractionally distil it through a short column packed with glass helices. It has apenetrating, mildly pungent odour with a high vapour pressure at room temperature. [Erickson & Spoerri J Am Chem Soc 68 400 1946, Hetman & O.Donnell J Org Chem 28 1682 1963, Beilstein 23/5 V 366.]
Properties of 2-Chloropyrazine
| Melting point: | 153～154℃ |
| Boiling point: | 153-154 °C (lit.) |
| Density | 1.283 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 136 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in Methanol |
| form | Liquid |
| pka | -1.10±0.10(Predicted) |
| Specific Gravity | 1.283 |
| color | Clear colorless to yellow |
| Water Solubility | INSOLUBLE |
| BRN | 107019 |
| CAS DataBase Reference | 14508-49-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Chloropyrazine(14508-49-7) |
| EPA Substance Registry System | Pyrazine, chloro- (14508-49-7) |
Safety information for 2-Chloropyrazine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P370+P378:In case of fire: Use … for extinction. |
Computed Descriptors for 2-Chloropyrazine
2-Chloropyrazine manufacturer
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
You may like
-
14508-49-7 2-Chloropyrazine 98%View Details
14508-49-7 -
2-Chloropyrazine 98%View Details
14508-49-7 -
2-Chloropyrazine, 98% 99%View Details
14508-49-7 -
Chloropyrazine CAS 14508-49-7View Details
14508-49-7 -
2-Chloropyrazine CAS 14508-49-7View Details
14508-49-7 -
144-83-2 Sulfapyridine 98+View Details
144-83-2 -
29976-53-2 98+View Details
29976-53-2 -
674783-97-2 98+View Details
674783-97-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.