2'-Chloro-4'-hydroxyacetophenone
- CAS NO.：41068-36-4
- Empirical Formula: C9H9ClO2
- Molecular Weight: 184.62
- MDL number: MFCD09027992
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:51:26
What is 2'-Chloro-4'-hydroxyacetophenone?
The Uses of 2'-Chloro-4'-hydroxyacetophenone
1-(2-Chloro-4-hydroxyphenyl)ethanone is used in preparation of aminopyrazine compounds as HPK1 inhibitor and the use thereofof aminopyrazine compounds as HPK1 inhibitor and the use thereof.
Preparation
Obtained by reaction of acetyl chloride with 3-chloroanisole in the presence of aluminium chloride (55%), in carbon disulfide (62%) or in 1,2-dichloroethane (81%).
Properties of 2'-Chloro-4'-hydroxyacetophenone
| Melting point: | 26–27°C |
| Boiling point: | 151 °C(Press: 12 Torr) |
| Density | 1.176±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| color | Clear, light orange |
Safety information for 2'-Chloro-4'-hydroxyacetophenone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2'-Chloro-4'-hydroxyacetophenone
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
![(E)-1-[2-CHLORO-4-(4-CHLOROPHENOXY)PHENYL]-3-PHENYL-2-PROPEN-1-ONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB7305546.gif)
![ETHYL 4-(4-[2-CHLORO-4-(4-CHLOROPHENOXY)BENZOYL]-1H-1,2,3-TRIAZOL-1-YL)BENZENECARBOXYLATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB9758719.gif)
![2-((2-[2-CHLORO-4-(4-CHLOROPHENOXY)PHENYL]-2-OXOETHYL)SULFANYL)-1-PYRIDINIUMOLATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB4208976.gif)
METHANONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB9188143.gif)
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