2-Bromo-4-(trifluoromethyl)pyridine
- CAS NO.：175205-81-9
- Empirical Formula: C6H3BrF3N
- Molecular Weight: 225.99
- MDL number: MFCD00153085
- EINECS: 672-057-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:33:00
What is 2-Bromo-4-(trifluoromethyl)pyridine?
The Uses of 2-Bromo-4-(trifluoromethyl)pyridine
2-Bromo-4-(trifluoromethyl)pyridine in used in the preparation of pyrazolopyridines as kinase LRRK2 inhibitors for treating and preventing cancer and neurodegenerative diseases.
The Uses of 2-Bromo-4-(trifluoromethyl)pyridine
Regioselective deprotonation at C-3 with LDA followed by trapping with carbon dioxide provides the correspondin nicotinic acid.
Properties of 2-Bromo-4-(trifluoromethyl)pyridine
| Melting point: | -21--20 °C |
| Boiling point: | 84-85 °C/14 mmHg |
| Density | 1.827 g/mL at 25 °C |
| refractive index | n |
| Flash point: | 164 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | -1.57±0.10(Predicted) |
| color | Colorless to Light yellow to Light orange |
| CAS DataBase Reference | 175205-81-9(CAS DataBase Reference) |
Safety information for 2-Bromo-4-(trifluoromethyl)pyridine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Bromo-4-(trifluoromethyl)pyridine
| InChIKey | WZVHLUMAQLUNTJ-UHFFFAOYSA-N |
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