2-(AMINOMETHYL)-18-CROWN-6
Synonym(s):1,4,7,10,13,16-Hexaoxacyclooctadecane-2-methanamine
- CAS NO.：83585-61-9
- Empirical Formula: C13H27NO6
- Molecular Weight: 293.36
- MDL number: MFCD00191741
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:29
What is 2-(AMINOMETHYL)-18-CROWN-6?
The Uses of 2-(AMINOMETHYL)-18-CROWN-6
2-Aminomethyl-18-crown-6 (AM-18-C-6) can be used to prepare:
- AM-18-C-6 bonded Merrifield peptide resin, which is used to study the absorption and the isotopic effect of magnesium.
- Schiff base of gossypol with aminomethyl crown ether for complexation of monovalent cations.
- Crown tagged triarylphosphine by reacting with triphenylphosphine carboxylic acid. These tagged triarylphosphine reagents are used in Mitsunobu and Heck reactions for the removal of phosphine derived by-products.
- 1,16-hexadecanoyl-bis-(2-aminomethyl)-18-crown-6 (bola A-16), which is utilized as a vesicular carrier in a drug delivery system.
Properties of 2-(AMINOMETHYL)-18-CROWN-6
| Boiling point: | 135 °C/0.08 mmHg (lit.) |
| Density | 1.126 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.479(lit.) |
| Flash point: | 113 °C |
| pka | 9.11±0.29(Predicted) |
| BRN | 4184588 |
Safety information for 2-(AMINOMETHYL)-18-CROWN-6
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(AMINOMETHYL)-18-CROWN-6
New Products
Cyclopentane-1,2-dione 8-hydroxy-7-methoxy-2,6-dimethylisoquinolinium iodide Isopropyl amine Hydrochloride 3-Aminophenylacetic acid 2-Bromo-5-iodopyridine 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Amino-4-methoxyben-zeneacetic acid 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide valeronitrile 3-Hydroxypropionitrile 4-Bromo Benzylcyanide 3-chlorobenzyl cyanide 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioate (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinateRelated products of tetrahydrofuran
![2-[2-(3-aminopropoxy)ethoxy]ethanol](https://img.chemicalbook.in/CAS/GIF/112-33-4.gif)
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