2-Amino-5-fluoropyridine
- CAS NO.：21717-96-4
- Empirical Formula: C5H5FN2
- Molecular Weight: 112.11
- MDL number: MFCD01861120
- EINECS: 627-638-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 2-Amino-5-fluoropyridine?
Chemical properties
Light yellow Cryst
The Uses of 2-Amino-5-fluoropyridine
2-Amino-5-fluoropyridine is used in chemical microarrays to identify ligands that binds pathogenic cells. Acts as a reagent in the preparation of heterocyclic compounds as integrase inhibiting antiviral agents.
Definition
ChEBI: 2-Amino-5-fluoropyridine is a dihydropyridine.
Synthesis
2-Amino-5-fluoropyridine is an important intermediate for the synthesis of LBM415 which is the peptide deformylas inhibitor. Using 2-aminopyridine as raw material and via nitrification, amino acetylation, reduction of nitro, diazolization, Schiemann reaction and hydrolysis of acetyl.
Properties of 2-Amino-5-fluoropyridine
| Melting point: | 93-97 °C (lit.) |
| Boiling point: | 125 °C |
| Density | 1.257±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Methanol |
| pka | 4.62±0.13(Predicted) |
| form | Powder |
| color | White to orange |
| BRN | 385938 |
| InChI | InChI=1S/C5H5FN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8) |
| CAS DataBase Reference | 21717-96-4(CAS DataBase Reference) |
Safety information for 2-Amino-5-fluoropyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-5-fluoropyridine
| InChIKey | YJTXQLYMECWULH-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(F)C=C1 |
2-Amino-5-fluoropyridine manufacturer
JSK Chemicals
2Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 2-Amino-5-fluoropyridine, 97% 99%
Lorven Biologics Pvt Ltd
1Y
Phone:+91-8884110005
Whatsapp: +91-8884110005
product: 2-amino 5-fluoro pyridine 21717-96-4 98%
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