Flupirtine
- CAS NO.：56995-20-1
- Empirical Formula: C15H17FN4O2
- Molecular Weight: 304.32
- MDL number: MFCD00864265
- EINECS: 260-503-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-28 16:00:23
What is Flupirtine?
The Uses of Flupirtine
Therapeutic use of Flupirtine was discontinued due to drug induced liver injury (DILI). Since the mechanism of action is not related to its adverse effects, it is important to focus on chemical modifications.
The Uses of Flupirtine
Analgesic.
Definition
ChEBI: N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester is an aminopyridine.
Clinical Use
Flupirtine maleate is an analgesic with an unknown mode of action. It is used in single doses of 100 mg orally and 150 mg rectally for the treatment of different pain conditions.
Properties of Flupirtine
| Melting point: | 115-116° |
| Boiling point: | 445.15°C (rough estimate) |
| Density | 1.350±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 12.19±0.70(Predicted) |
| Water Solubility | 1g/L(temperature not stated) |
Safety information for Flupirtine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Flupirtine
Flupirtine manufacturer
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