2-Amino-4-chloro-6-methylpyrimidine
- CAS NO.：5600-21-5
- Empirical Formula: C5H6ClN3
- Molecular Weight: 143.57
- MDL number: MFCD00006091
- EINECS: 227-018-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:15
What is 2-Amino-4-chloro-6-methylpyrimidine?
Chemical properties
WHITE TO LIGHT YELLOW NEEDLE-LIKE CRYST. POWDER
The Uses of 2-Amino-4-chloro-6-methylpyrimidine
2-Amino-4-chloro-6-methylpyrimidine was used to study the influence of chlorine substitution in pyrimidine ring on proton donor ability of amino group in 2-aminopyrimidine.
Definition
ChEBI: An aminopyrimidine compound having its amino group at position 2 and chloro and methyl substituents at positions 4 and 6 respectively.
General Description
2-Amino-4-chloro-6-methylpyrimidine is a nitification inhibitor.
Purification Methods
Recrystallise it from EtOH. [Beilstein 24 H 84.]
Properties of 2-Amino-4-chloro-6-methylpyrimidine
| Melting point: | 183-186 °C (lit.) |
| Boiling point: | 234.32°C (rough estimate) |
| Density | 1.2986 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | acetic acid: soluble50mg/mL, clear, colorless to faintly yellow |
| form | Solid |
| pka | 4.26±0.10(Predicted) |
| color | White to Off-White |
| Water Solubility | Insoluble in water. |
| BRN | 114297 |
| CAS DataBase Reference | 5600-21-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Amino-4-chloro-6-methylpyrimidine(5600-21-5) |
Safety information for 2-Amino-4-chloro-6-methylpyrimidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Amino-4-chloro-6-methylpyrimidine
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
![3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-(3-[(PHENYLTHIO)METHYL]BENZOYL)ACRYLONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2311263.gif)
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