2-Amino-3,5-dibromopyrazine
- CAS NO.：24241-18-7
- Empirical Formula: C4H3Br2N3
- Molecular Weight: 252.89
- MDL number: MFCD00673150
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:58
What is 2-Amino-3,5-dibromopyrazine?
Chemical properties
white to light yellow crystal powde
The Uses of 2-Amino-3,5-dibromopyrazine
2-Amino-3,5-dibromopyrazine may be used in the synthesis of:
- 2-amino-5-bromopyrazin-3-thiol
- 2-amino-3,5-bis(p-methoxyphenyl)-1,4-pyrazine
- 3,7-dihydroimidazo[1,2a]pyrazine-3-ones
The Uses of 2-Amino-3,5-dibromopyrazine
2-Amino-3,5-dibromopyrazine is used in the preparation of conjugated polymers for neurotoxin detection. 2-Amino-3,5-dibromopyrazine is an intermediate in the preparation of rho kinase (ROCK) inhibitor s.
General Description
2-Amino-3,5-dibromopyrazine can be synthesized from 2-aminopyrazine via bromination using N-bromosuccinimide (NBS). It reacts with sodium dicyanocuprate to form a mixture of mono and dicyanation products. The formation of 2-aminothiazolopyrazines by reacting 2-amino-3,5-dibromopyrazine with isothiocyanates has been reported.
Properties of 2-Amino-3,5-dibromopyrazine
| Melting point: | 114-117 °C (lit.) |
| Boiling point: | 294.6±35.0 °C(Predicted) |
| Density | 2.287±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | soluble in Methanol |
| form | Powder |
| pka | 0.81±0.10(Predicted) |
| color | Yellow to brown |
| CAS DataBase Reference | 24241-18-7(CAS DataBase Reference) |
Safety information for 2-Amino-3,5-dibromopyrazine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-3,5-dibromopyrazine
| InChIKey | DTLBKXRFWUERQN-UHFFFAOYSA-N |
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