2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

Synonym(s):2-Amino-1,1-3-tricyanopropene;Malononitrile dimer

CAS NO.：868-54-2
Empirical Formula: C6H4N4
Molecular Weight: 132.12
MDL number: MFCD00001851
EINECS: 212-777-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE Structural

What is 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE?

Chemical properties

light pink to beige or light brownish. 2-Amino-1-propene-1,1,3-tricarbonitrile [868-54-2], 2-amino-1,1,3-tricyanopropene, malononitrile dimer, (NC)2C=C (NH2) CH2CN, Mr 132.13, mp 171 – 173℃, is a light brownish powder, insoluble in water.

The Uses of 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

2-Amino-1,1,3-propenetricarbonitrile stimulates choline acetyltransferase activity in animals. A neurotrophic agent with potential therapeutic effect on cholinergic disorders.

Biochem/physiol Actions

2-Amino-1,1,3-propenetricarbonitrile is a key intermediate in synthesis of various heterocyclic compounds. 2-Amino-1,1-3-tricyanopropene undergoes condensation reaction with aromatic nitroso compounds to form useful coloring agents. 2-Amino-1,1-3-tricyanopropene reacts with 1,3-dithiole-derived polyenals to form push–pull systems with (Z)-geometry around the newly formed carbon-carbon double bond.

Synthesis

Malononitrile dimer is obtained from the base-catalyzed dimerization of malononitrile. It has been investigated as a potential precursor for new dyes but it has no current industrial significance.

Properties of 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

Melting point:	171-173 °C (lit.)
Boiling point:	234.02°C (rough estimate)
Density	1.262
refractive index	1.7000 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	powder to crystal
pka	-2.92±0.70(Predicted)
color	White to Gray to Brown
Merck	14,480
BRN	1756131
CAS DataBase Reference	868-54-2(CAS DataBase Reference)

Safety information for 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

Signal word	Warning
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…