O4I1
- CAS NO.：175135-47-4
- Empirical Formula: C16H15NO2
- Molecular Weight: 253.3
- MDL number: MFCD00067778
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:55:37
What is O4I1?
Description
O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.
The Uses of O4I1
O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.
Properties of O4I1
| Boiling point: | 424.5±30.0 °C(Predicted) |
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly |
| form | A crystalline solid |
| color | Light yellow to yellow |
Safety information for O4I1
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P222:Do not allow contact with air. P231:Handle under inert gas. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P422:Store contents under … P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for O4I1
New Products
1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D BENZENE-D6 TOLUENE-D3 2-Hydroxybutanenitrile 1-Benzylindolin-2-one Ethyl 2-bromo-3-oxobutanoate 4-(3-chloropropyl)morpholine 1-Benzylindoline-2,3-dione 3-Oxocyclobutanecarboxylic acid 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![{4-[(3-methoxybenzyl)oxy]phenyl}acetonitrile](https://img.chemicalbook.in/CAS/20200401/GIF/CB91605557.gif)
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