2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
- CAS NO.:175135-47-4
- Empirical Formula: C16H15NO2
- Molecular Weight: 253.3
- MDL number: MFCD00067778
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-20 16:56:10
What is 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE?
Description
O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.
The Uses of 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.
Properties of 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
| Boiling point: | 424.5±30.0 °C(Predicted) |
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly |
| form | A crystalline solid |
| color | Light yellow to yellow |
Safety information for 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P222:Do not allow contact with air. P231:Handle under inert gas. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P422:Store contents under … P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
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