2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
- CAS NO.：115199-84-3
- Empirical Formula: C21H25Cl3N2O
- Molecular Weight: 427.8
- MDL number: MFCD01074479
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
![2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE Structural](https://img.chemicalbook.in/CAS/GIF/115199-84-3.gif)
What is 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE?
The Uses of 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
Opioid agonists exert a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. ICI 199441 is a selective κ-opioid agonist with analgesic properties.
What are the applications of Application
ICI-199,441 hydrochloride is a highly potent KOR (κ-opioid receptor agonist
Biological Activity
Highly potent κ agonist, 146-fold more active than U-50488 (trans-(?-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride ) in vitro .
Storage
Store at RT
Properties of 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
| storage temp. | Store at RT |
| solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| form | White solid. |
| color | White to off-white |
Safety information for 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
Computed Descriptors for 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
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