2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonym(s):N-Boc-2-(2-hydroxymethyl)piperidine;1-tert-Butoxycarbonyl-2-piperidineethanol;2-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
- CAS NO.：118811-03-3
- Empirical Formula: C12H23NO3
- Molecular Weight: 229.32
- MDL number: MFCD03701252
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:16:16
What is 2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER?
The Uses of 2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Reactant for synthesis of:
- Vasopressin1b receptor antagonists
- CXCR4 antagonists as anti-HIV agents
- Coumarin-based inhibitors of inducible nitric oxide synthase
- Selective thrombin inhibitors
Reactant for:
- N-directed hydroboration for synthesis of amino alcohols
- Enantioselective synthesis of sedamine and allosedamine
Properties of 2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
| Boiling point: | 100-110 °C/0.3 mmHg |
| Density | 1.032 g/mL at 25 °C |
| refractive index | n20/D 1.472 |
| Flash point: | 110 °C |
| pka | 15.15±0.10(Predicted) |
| CAS DataBase Reference | 118811-03-3(CAS DataBase Reference) |
Safety information for 2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for 2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
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