1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
Synonym(s):1a,10b-Dihydro-6H-dibenzo(b,f)oxireno[d]azepine-6-carboxamide
- CAS NO.：36507-30-9
- Empirical Formula: C15H12N2O2
- Molecular Weight: 252.27
- MDL number: MFCD00467137
- EINECS: 641-693-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-07 19:09:50
![1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Structural](https://img.chemicalbook.in/CAS/GIF/36507-30-9.gif)
What is 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE?
Chemical properties
White Solid
The Uses of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.
The Uses of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC
The Uses of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.
What are the applications of Application
Carbamazepine 10,11-Epoxide is a Carbamazepine metabolite
Definition
ChEBI: An epoxide and metabolite of carbamazepine.
General Description
Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.
Biochem/physiol Actions
First metabolite of carbamazepine
Properties of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
| Melting point: | 204-206°C |
| Boiling point: | 390.2±52.0 °C(Predicted) |
| Density | 1.377±0.06 g/cm3(Predicted) |
| Flash point: | 9℃ |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| form | neat |
| pka | 13.91±0.20(Predicted) |
| form | Solid |
| color | White |
Safety information for 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
| Signal word | Danger |
| Pictogram(s) |
 Environment GHS09 |
| GHS Hazard Statements |
H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
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![5H-Dibenz[b,f]azepine-5-carboxamide dihydrate](https://img.chemicalbook.in/CAS/20180629/GIF/85756-57-6.gif)
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