10,11-DIHYDROCARBAMAZEPINE
Synonym(s):10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide;10,11-Dihydrocarbamazepine
- CAS NO.：3564-73-6
- Empirical Formula: C15H14N2O
- Molecular Weight: 238.28
- MDL number: MFCD00005072
- EINECS: 222-649-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-14 16:49:18
What is 10,11-DIHYDROCARBAMAZEPINE?
Chemical properties
white crystals or needles
The Uses of 10,11-DIHYDROCARBAMAZEPINE
10,11-Dihydrocarbamazepine is used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It can be used in chemiluminescence method for determination of carbamazepine.
The Uses of 10,11-DIHYDROCARBAMAZEPINE
A dihydro impurity of Carbamazepine (C175840)
What are the applications of Application
10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug
General Description
10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.
Properties of 10,11-DIHYDROCARBAMAZEPINE
| Melting point: | 205-210 °C(lit.) |
| Boiling point: | 394.5±52.0 °C(Predicted) |
| Density | 1.232±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | dichloromethane: soluble2.5%, clear, colorless |
| form | neat |
| pka | 14.07±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in dichloromethane. Insoluble in water. |
| BRN | 196969 |
Safety information for 10,11-DIHYDROCARBAMAZEPINE
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin H336:Specific target organ toxicity,single exposure; Narcotic effects |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 10,11-DIHYDROCARBAMAZEPINE
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