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Home Product name list15(R)-ILOPROST

15(R)-ILOPROST

CAS NO.：85026-51-3
Empirical Formula: C22H32O4
Molecular Weight: 360.49
MDL number: MFCD05863932
SAFETY DATA SHEET (SDS)
Update Date: 2025-04-18 09:52:11

15(R)-ILOPROST Structural

What is 15(R)-ILOPROST?

Description

Iloprost is a second generation structural analog of prostacyclin (PGI₂) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP receptors with a K_i of 11 nM. 15(R)-Iloprost is the “unnatural” or inverted C-15 epimer of iloprost. This transformation frequently attenuates the biological agonist activity of prostaglandin analogs by several orders of magnitude. There are no literature reports of the biological activity of 15(R)-iloprost.

What are the applications of Application

15(R)-Iloprost is a second generation structural analog of prostacyclin

Properties of 15(R)-ILOPROST

solubility

DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml

Safety information for 15(R)-ILOPROST

Computed Descriptors for 15(R)-ILOPROST

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15(R)-ILOPROST

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