1,4-Diacryloylpiperazine

Synonym(s):PDA;BAP;Piperazine diacrylamide;1,4-Bis(acryloyl)piperazine;1,4-Di(acryloyl)piperazine

CAS NO.：6342-17-2
Empirical Formula: C10H14N2O2
Molecular Weight: 194.23
MDL number: MFCD00077661
EINECS: 613-215-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:59:04

What is 1,4-Diacryloylpiperazine?

Chemical properties

Off-white solid

The Uses of 1,4-Diacryloylpiperazine

1,4-Diacryloylpiperazine is used as a crosslinker in polyacrylamide gels. PIP provides polyacrylamide gels with increased physical strength and improved separation and detection of proteins

The Uses of 1,4-Diacryloylpiperazine

Used as a crosslinker in polyacrylamide gels. PIP provides polyacrylamide gels with increased physical strength and improved separation and detection of proteins.

The Uses of 1,4-Diacryloylpiperazine

Suitable for preparation of gels for PAGE, IEF, 2D electrophoresis and protein sequencing.

What are the applications of Application

1,4-Bis(acryloyl)piperazine is a polyacrylamide gel cross-linker used to reduces silver-staining background

Definition

ChEBI: 1-[4-(1-oxoprop-2-enyl)-1-piperazinyl]-2-propen-1-one is a N-acylpiperazine and a tertiary carboxamide.

General Description

1,4-Bis(acryloyl)piperazine is a reagent that can be substituted for bis-acrylamide in the preparation of polyacrylamide gels.

Properties of 1,4-Diacryloylpiperazine

Melting point:	91.5-93.5 °C(lit.)
Boiling point:	434.1±25.0 °C(Predicted)
Density	1.114±0.06 g/cm3(Predicted)
RTECS	UD6715000
storage temp.	room temp
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	-0.70±0.70(Predicted)
form	powder
BRN	745431
CAS DataBase Reference	6342-17-2(CAS DataBase Reference)

Safety information for 1,4-Diacryloylpiperazine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.