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Home Product name list13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2

13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2

CAS NO.：59894-07-4
Empirical Formula: C20H32O5
Molecular Weight: 352.47
MDL number: MFCD00885499
SAFETY DATA SHEET (SDS)
Update Date: 2025-08-21 14:05:29

13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2 Structural

What is 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2?

Description

13,14-dihydro-15-keto Prostaglandin D₂ (13,14-dihydro-15-keto PGD₂) is a metabolite of PGD₂ which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD₂ was recently identified as a selective agonist for the CRTH2/DP₂ receptor. It also inhibits ion flux in a canine colonic mucosa preparation. In humans, 13,14-dihydro-15-keto PGD₂ is further metabolized to give 11β-hydroxy compounds which have also undergone β-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD₂ survives intact in the urine.

The Uses of 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2

13,14-Dihydro-15-keto-PGD2 is a metabolite of Prostaglandin D2 (CAT# P838575) and a selective CRTh2/DP2 receptor agonist. CRTh2/DP2 receptors play crucial roles in atopic dermatitis, asthma, and other inflammatory diseases.

What are the applications of Application

13,14-dihydro-15-keto Prostaglandin D2 is a selective DP2 receptor agonist

Definition

ChEBI: 13,14-dihydro-15-ketoprostaglandin D2 is a prostaglandins D. It has a role as a metabolite. It is functionally related to a prostaglandin D2.

Properties of 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2

Boiling point:	542.1±40.0 °C(Predicted)
Density	1.086±0.06 g/cm3(Predicted)
pka	4.76±0.10(Predicted)

Safety information for 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2

Computed Descriptors for 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2

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