(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE
- CAS NO.：180675-22-3
- Empirical Formula: C4H7BrMgO2
- Molecular Weight: 191.31
- MDL number: MFCD01321271
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:03:03
What is (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE?
The Uses of (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE
(1,3-Dioxolan-2-ylmethyl)magnesium bromide is a Grignard reagent that can be used to prepare:
- 3-[11C]-Propionaldehyde, a key intermediate for the synthesis of radiolabeled compound [11C]SN-38, wherein SN-38 is 7-ethyl-10-hydroxy camptothecin.
- 1-[(S)-2,2-Dimethyl-(1,3)-dioxolan-4-yl]-4-(1,3-dioxolan2-yl)-2-ol by reacting with D-glyceraldehyde, which is further used to synthesize unsaturated nucleosides.
- A bicyclo carboxylate intermediate, which is employed in the total synthesis of spirovibsanin A.
Properties of (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE
| Boiling point: | 65-67 °C |
| Density | 0.938 g/mL at 25 °C |
| Flash point: | −4 °F |
| form | Powder |
| color | White to off-white to pale brown |
Safety information for (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE
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