1,2,3,6-TETRAHYDROPYRIDINE

CAS NO.：694-05-3
Empirical Formula: C5H9N
Molecular Weight: 83.13
MDL number: MFCD00005949
EINECS: 211-766-2
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 1,2,3,6-TETRAHYDROPYRIDINE?

Chemical properties

Clear colorless to pale yellow liquid

The Uses of 1,2,3,6-TETRAHYDROPYRIDINE

Organic intermediate.

The Uses of 1,2,3,6-TETRAHYDROPYRIDINE

Used to form ene-endo-spirocyclic ammonium ylids for [2,3]-sigmatropic rearrangement to pyrroloazepinones and oxazepinones.

What are the applications of Application

1,2,3,6-Tetrahydropyridine is used to form ene-endo-spirocyclic ammonium ylids

Definition

ChEBI: 3-piperideine is a piperideine.

General Description

A colorless liquid. Density 0.913 g / cm3 and insoluble in water. Hence floats on water. Flash point near 110°F. Vapors heavier than air. Used to make other chemicals.

Air & Water Reactions

Flammable. Insoluble in water.

Reactivity Profile

1,2,3,6-TETRAHYDROPYRIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Properties of 1,2,3,6-TETRAHYDROPYRIDINE

Melting point:	−48 °C(lit.)
Boiling point:	108 °C(lit.)
Density	0.911 g/mL at 25 °C(lit.)
refractive index	n20/D 1.48(lit.)
Flash point:	61 °F
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	10.22±0.10(Predicted)
form	Powder
color	White to pale yellow-cream
Stability:	Light Sensitive
CAS DataBase Reference	694-05-3(CAS DataBase Reference)
EPA Substance Registry System	Pyridine, 1,2,3,6-tetrahydro- (694-05-3)

Safety information for 1,2,3,6-TETRAHYDROPYRIDINE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.