1,2,3,4-Tetramethylbenzene
- CAS NO.：488-23-3
- Empirical Formula: C10H14
- Molecular Weight: 134.22
- MDL number: MFCD00008521
- EINECS: 207-673-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:23:09
What is 1,2,3,4-Tetramethylbenzene?
Chemical properties
Colorless liquid. Soluble in alcohol; insoluble in water.
The Uses of 1,2,3,4-Tetramethylbenzene
1,2,3,4-Tetramethylbenzene is a useful starting material and building block for organic synthesis. An analyte identified in the volatile oils from Taxodium ascendens leaves and cones. Antibacterial activity.
Definition
ChEBI: A tetramethylbenzene that consists of benzene substituted by methyl groups at positions 1, 2, 3 and 4.
Purification Methods
Dry it over sodium and distil under reduced pressure. The picrate has m 92-95o (EtOH). [Beilstein 5 H 430, 5 I 206. 5 II 329, 5 III 974, 5 IV 1072.]
Properties of 1,2,3,4-Tetramethylbenzene
| Melting point: | 76-80 °C(lit.) |
| Boiling point: | 203°C |
| Density | 0.838 g/mL at 25 °C(lit.) |
| vapor density | 4.6 (vs air) |
| vapor pressure | 160 mm Hg ( 140 °C) |
| refractive index | 1.5190 |
| Flash point: | 165 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless |
| Odor Threshold | 0.011ppm |
| Water Solubility | Immiscible with water. |
| BRN | 1904390 |
| Dielectric constant | 2.5899999999999999 |
| CAS DataBase Reference | 488-23-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1,2,3,4-tetramethyl-(488-23-3) |
| EPA Substance Registry System | 1,2,3,4-Tetramethylbenzene (488-23-3) |
Safety information for 1,2,3,4-Tetramethylbenzene
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 1,2,3,4-Tetramethylbenzene
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