1,2-Dihydro-2,2,4-trimethylquinoline

CAS NO.：147-47-7
Empirical Formula: C12H15N
Molecular Weight: 173.25
MDL number: MFCD00044248
EINECS: 205-688-8
SAFETY DATA SHEET (SDS)
Update Date: 2025-06-13 14:48:16

What is 1,2-Dihydro-2,2,4-trimethylquinoline?

The Uses of 1,2-Dihydro-2,2,4-trimethylquinoline

1,2-Dihydro-2,2,4-trimethylquinoline is used as an antioxidant in styrene-butadiene and nitrile-butadiene rubbers and latexes. It was selected for evaluation because it is a derivative of quinoline, a known rodent carcinogen, and was regarded as having potential carcinogenic activity.

The Uses of 1,2-Dihydro-2,2,4-trimethylquinoline

1,2-Dihydro-2,2,4-trimethylquinoline (>85%) is used as an antioxidant in styrene-butadiene and nitrile-butadiene rubbers and latexes. It was selected for evaluation because it is a derivative of quinoline, a known rodent carcinogen, and was regarded as having potential carcinogenic activity.

General Description

Dark cloudy copper-colored or yellow liquid. Odorless.

Air & Water Reactions

1,2-Dihydro-2,2,4-trimethylquinoline may be sensitive to prolonged exposure to air and light. . Insoluble in water.

Reactivity Profile

1,2-Dihydro-2,2,4-trimethylquinoline neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 1,2-Dihydro-2,2,4-trimethylquinoline emits toxic fumes of nitrogen oxides.

Fire Hazard

1,2-Dihydro-2,2,4-trimethylquinoline is combustible.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.

Properties of 1,2-Dihydro-2,2,4-trimethylquinoline

Melting point:	120 °C
Boiling point:	293.92°C (rough estimate)
Density	1.0215 (rough estimate)
refractive index	1.5680 (estimate)
storage temp.	2-8°C(protect from light)
solubility	Chloroform (Soluble), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Spari
form	Oil
pka	4.16±0.70(Predicted)
color	Brown to Very Dark Brown
Stability:	Light Sensitive
CAS DataBase Reference	147-47-7(CAS DataBase Reference)
EPA Substance Registry System	1,2-Dihydro-2,2,4-trimethylquinoline (147-47-7)

Safety information for 1,2-Dihydro-2,2,4-trimethylquinoline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.