10-Nitrocamptothecin
- CAS NO.：86639-62-5
- Empirical Formula: C20H15N3O6
- Molecular Weight: 393.35
- MDL number: MFCD06656294
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-04 15:29:52
What is 10-Nitrocamptothecin?
The Uses of 10-Nitrocamptothecin
Whether cells can divide depends on the two key points of entering S phase and M phase. Studies have found that 10-Nitrocamptothecin can induce apoptosis. After administration, both S phase and G2M phase of cell growth are delayed. Inhibition occurred throughout the cell cycle and was found to be dose- and time-dependent.
Definition
ChEBI: Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone.
Properties of 10-Nitrocamptothecin
| Boiling point: | 827.4±65.0 °C(Predicted) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| pka | 11.17±0.20(Predicted) |
Safety information for 10-Nitrocamptothecin
Computed Descriptors for 10-Nitrocamptothecin
New Products
DL-beta-(3-Bromophenyl)alanine 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Amlodipine EP Impurity-C Budesonide Impurity-K/Budesonide 21-Acetate (Epimers) Gabapentine Impurity 72 Bicalutamide Impurity-B Betahistine EP Impurity C Carbamazepine EP Impurity G 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3-Hydroxypropionitrile 4-Bromo Benzylcyanide valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
![2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one](https://img.chemicalbook.in/CAS/20150408/GIF/526-43-2.gif)
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