10-Nitrocamptothecin
- CAS NO.：86639-62-5
- Empirical Formula: C20H15N3O6
- Molecular Weight: 393.35
- MDL number: MFCD06656294
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-04 15:29:52
What is 10-Nitrocamptothecin?
The Uses of 10-Nitrocamptothecin
Whether cells can divide depends on the two key points of entering S phase and M phase. Studies have found that 10-Nitrocamptothecin can induce apoptosis. After administration, both S phase and G2M phase of cell growth are delayed. Inhibition occurred throughout the cell cycle and was found to be dose- and time-dependent.
Definition
ChEBI: Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone.
Properties of 10-Nitrocamptothecin
| Boiling point: | 827.4±65.0 °C(Predicted) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| pka | 11.17±0.20(Predicted) |
Safety information for 10-Nitrocamptothecin
Computed Descriptors for 10-Nitrocamptothecin
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