1-O-HEXADECYL-SN-GLYCEROL
Synonym(s):1-O-hexadecyl-sn-glycerol (HG)
- CAS NO.：506-03-6
- Empirical Formula: C19H40O3
- Molecular Weight: 316.52
- MDL number: MFCD00151171
- EINECS: 208-026-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is 1-O-HEXADECYL-SN-GLYCEROL?
Description
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.
The Uses of 1-O-HEXADECYL-SN-GLYCEROL
1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.
What are the applications of Application
1-O-Hexadecyl-sn-glycerol is a naturally occuring ether lipid
Definition
ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound.
Purification Methods
Recrystallise it from hexane. [Beilstein 1 III 2322.]
Properties of 1-O-HEXADECYL-SN-GLYCEROL
| Melting point: | 64° |
| Boiling point: | bp0.005 120° |
| alpha | D20 +3.0° (c = 1.16 in chloroform) |
| Density | 1.0054 (rough estimate) |
| refractive index | 1.4410 (estimate) |
| storage temp. | -15°C |
| solubility | DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| pka | 13.68±0.20(Predicted) |
Safety information for 1-O-HEXADECYL-SN-GLYCEROL
Computed Descriptors for 1-O-HEXADECYL-SN-GLYCEROL
New Products
Ivermectin Ep Impurity- k Cyclopropane-1,1-dicarboxylic acid [1]Benzothieno[2,3-c]pyridine, 1,7-dichloro-8-methyl- (S)-3-Fluoro-pyrrolidine hydrochloride Cyclobutylamine 1-Bromo-2-Methoxy-3-Nitrobenzene 3-Oxocyclobutane-1-carboxylicacid (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo [2,3-d]pyrimidine-6-carbox amide 4-amino-2-fluoro-N- methylbenzamide N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one 4-Bromo-2-fluoro-N-methylbenzamide N-Boc-1,4-butanediamine 4-Dimethylamino pyridine 2-Chlorotrityl Chloride 4-Bromoaniline 5-Bromo-2-chlorobenzoic acid 1,2,3,9-Tetrahydro-4(H)-carbazol-4-oneRelated products of tetrahydrofuran
![1,2-DIOCTADECANOYL-SN-GLYCERO-3-PHOSPHO-RAC-[1-GLYCEROL] AMMONIUM SALT](https://img.chemicalbook.in/CAS/GIF/108347-80-4.gif)
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